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Avontec GmbH Fraunhoferstrasse 15 82152 Martinsried, Germany http://www.avontec.com
Contact AVONTEC GmbH +49 89 85651600
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Avontec GmbH

AVONTEC announce results of a multiple dose clinical proof of concept study with its drug candidate AVT-01 decoy ODN in asthmatic patients

(PresseBox) (Martinsried/Munich, )
AVONTEC GmbH, a privately held biopharmaceutical company dedicated to the development of novel therapies for chronic inflammatory diseases, today announced the results of a multiple dose, double-blind, randomized, placebo-controlled, multicenter, multinational, unbalanced, parallel-group comparison study with its lead drug candidate AVT-01 decoy oligonucleotide (AVT-01 decoy ODN) in asthmatic patients. In this study, the excellent safety profile of AVT-01 decoy ODN was again confirmed. However, efficacy (statistical significant reduction of airway hyper-responsiveness) as seen before in a single dose randomized, double-blind, placebo-controlled, monocenter cross-over pilot phase IIa study with AVT-01 decoy ODN could not be confirmed.

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