Billions of injections are administered worldwide on an annual basis. Nonetheless, the conventional approach via hypodermic needles is problematic due to risks involved with needle injuries, pain perception, and skin transport barrier limits. Intended as a minimally invasive and painless system, microneedle arrays (MNA) are an ideal solution for the transdermal delivery of drugs. Its ability to bypass the stratum corneum makes it a superior alternative to subcutaneous injections or other types of transdermal delivery systems such as chemical enhancers or microparticles. The primary objective of microneedles is to penetrate the skin with microscopic holes and disrupt the stratum corneum.
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