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Albert-Ludwigs-Universität Freiburg Friedrichstraße 39 79085 Freiburg, Germany http://www.uni-freiburg.de
Contact Ms Tanja Kaufmann 0761/203-4205
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Albert-Ludwigs-Universität Freiburg

Ionenkanal-Superkomplexe - neue Proteinmaschinen der Neurobiologie

Freiburger Wissenschaftler klären die rätselhafte Verbindung von Kalzium- und Kaliumkanälen in Nervenzellen auf

(PresseBox) (Freiburg, )
Forscher der Universitat Freiburg berichten in der fuhrenden Wissenschaftszeitschrift Science (Band 314, Seiten 615-620) uber die Entdeckung eines molekularen "Superkomplexes" aus einem Kalzium- und einem Kaliumkanal, mit dessen Hilfe Nervenzellen des Gehirns ihre elektrische Aktivitat und die Freisetzung von Hormonen steuern. Diese Entdeckung entschlusselt eines der altesten Ratsel der Neurobiologie, wie namlich Kaliumkanale uber Kalziumionen gesteuert werden konnen, ohne dass sich die Nervenzellen dabei selbst schadigen. Die Bedeutung dieser Arbeit wurde von der Wissenschaftszeitschrift durch die Veroffentlichung als Science Research Article besonders hervorgehoben.

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