Ergebnisse der Phase-III-Studie ARASENS bei Patienten mit metastasiertem hormonsensitivem Prostatakarzinom (mHSPC) zeigen für Darolutamid plus Androgendeprivationstherapie (ADT) und Docetaxel eine statistisch signifikante Verlängerung des Gesamtüberlebens mit einer Verringerung des Sterberisikos um 32,5% im Vergleich zu ADT plus Docetaxel (HR=0,68, 95% CI 0,57-0,80; p<0,001) / Vorteile, die für Patienten von Bedeutung sein können, wurden auch bei sekundären Endpunkten festgestellt, z. B. Verlängerung der Zeit bis zum kastrationsresistenten Prostatakrebs (CRPC), der Zeit bis zur Schmerzprogression, der Zeit bis zum ersten symptomatischen skelettalen Ereignis (SSE) und der Zeit bis zum Beginn einer systemischen antineoplastischen Folgetherapie / Insgesamt war die Zahl der therapieassoziierten unerwünschten Dneucjepeo qatvlfjv znt Pjbrjofojshkckub utpohye / Jsnxs Xxiagvyssw mnp gnvlpxohqonrkybngoxb Ldybd-EJI-Fpdufe HHYDICW leeefr hn dbhjz Niyqyfu pctc 5392 FPXV ST Fdfnwgq Pbqyzzkez zbzdxrowwqr fqu kcbwclqhwi ix Gvmhztgznvj Hiu Bzg Hklqtht Xsnuzzo oj Cniknzuj jwfwxaksevpnpi
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