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Elinzanetant erreicht alle primären und sekundären Endpunkte in Phase-III-Studie OASIS 4 zur Behandlung therapiebedingter mittelschwerer bis schwerer vasomotorischer Symptome bei Brustkrebspatientinnen

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- In OASIS 4 erreichte Elinzanetant alle primären Endpunkte und zeigte im Vergleich zum Placebo eine statistisch signifikante Verringerung der Häufigkeit von mittelschweren bis schweren vasomotorischen Symptomen (VMS), die durch eine begleitende endokrine Therapie bei Frauen mit Hormonrezeptor-positivem Brustkrebs oder einem hohen Risiko dafür verursacht wurden
- Die Studie zeigte auch positive Ergebnisse bei sekundären Endpunkten mit einer Verringerung des Schweregrads der VMS in Woche 4 und 12, eine Verringerung der VMS-Häufigkeit in Woche 1 sowie Verbesserungen bei Schlafstörungen und der Lebensqualität
- Das Sicherheitsprofil über 52 Wochen stimmt im Allgemeinen mit den zuvor publizierten Daten bei postmenopausalen Frauen que IOC kkrmsjc
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