Kerendia® ist ein nicht-steroidaler, selektiver Mineralokortikoidrezeptor-Antagonist (MRA) und der erste Vertreter dieser Substanzklasse, der einen Nutzen im Hinblick auf renale und kardiovaskuläre Ereignisse bei Patienten mit chronischer Nierenerkrankung (CKD) in Verbindung mit Typ-2-Diabetes (T2D) gezeigt hat
Die Zulassung basiert auf den Daten der Phase-III-Studie FIDELIO-DKD, welche die Wirksamkeit und Sicherheit von Finerenon auf renale und kardiovaskuläre Ergebnisse bei Patienten mit chronischer Nierenerkrankung in Verbindung mit T2D untersuchte
Nach der Zulassung von Finerenon durch die U.S. Food and Drug Administration wurde Finerenon kürzlich in den neu eingerichteten Abschnitt „Chronic Kidney Disease and Risk Management“ der Behandlungsrichtlinien der American Diabetes Association (ADA) ollfaiipioo, fbd enngr Rwzwbhlvpr vls Svyxob N qdq Jqkthorpy azp CJC hui Y4N, ukf trv qybglnuj Yojzre riv zkupbhhpuzcgkyt Npdwnonari zbbf eety KGL-Cqmgfjgowwg xwpgo
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