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Phase-II-Studie für VEGF Trap-Eye zeigt positive Zwischenergebnisse bei altersbedingter Makula-Degeneration

Phase-II-Studie für VEGF Trap-Eye zeigt positive Zwischenergebnisse bei altersbedingter Makula-Degeneration Bayer HealthCare und Regeneron planen Start einer Phase-III-Studie im zweiten Halbjahr 2007

(PresseBox) (Leverkusen, )
Positive Ergebnisse zeigt die vorläufige Zwischenanalyse einer Phase-II-Studie mit VEGF Trap-Eye. Die Studie untersucht VEGF Trap-Eye zur Behandlung einer Form der feuchten altersbedingten Makula-Degeneration (AMD). Die Patienten wurden in fünf Gruppen unterteilt und erhielten verschiedene Dosierungen VEGF Trap-Eye entweder im Abstand von vier Wochen oder in einer Einzeldosis. Etwa die Hälfte der Teilnehmer hat die noch andauernde Studie beendet. Nach den dabei gewonnen Daten wird der primäre Endpunkt erreicht: eine statistisch signifikante Verringerung der Netzhautdicke. Die Sehschärfe, ein sekundärer Endpunkt der Studie, verbesserte sich ebenfalls signifikant. Detaillierte Ergebnisse der Zwischenanalyse werden auf einer medizinischen Fachtagung vorgestellt.

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