Die Bayer Schering Pharma AG und das kalifornische Unternehmen OncoMed Pharmaceuticals, Inc. wollen gemeinsam an der Erforschung, Entwicklung und Vermarktung neuartiger Therapeutika gegen Krebsstammzellen arbeiten. Dabei zielt die heute geschlossene Vereinbarung auf die Entwicklung von Hemmstoffen für einen bestimmten zellulären Informationsweg (sogenannte Wnt-Signaltransduktion), der möglicherweise für die Entwicklung von Krebszellen bedeutsam ist. Den Krebsstammzellen - einer Untergruppe der Tumorzellen - wird eine bedeutende Rolle bei der Entstehung, Metastasierung und dem Wiederauftreten von Krebs zugesprochen. Potenziell könnten Inhibitoren des Wnt-Signalweges für zahlreiche Tumorindikationen entwickelt werden.
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