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Deutsches Krebsforschungszentrum Im Neuenheimer Feld 280 69120 Heidelberg, Germany http://www.dkfz.de
Contact Ms Dr. Sibylle Kohlstädt +49 6221 422854
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Deutsches Krebsforschungszentrum

Antikörper wirkt gegen strahlenbedingte Lungenfibrose

(PresseBox) (Heidelberg, )
Bestrahlungen der Lunge führen oft zu irreversiblen bindegewebigen Veränderungen, die die Funktionsfähigkeit des Lungengewebes einschränken. Wissenschaftler im Deutschen Krebsforschungszentrum konnten diesen Prozess nun bei Mäusen mit einem Antikörper verhindern und sogar rückgängig machen.

Bei etwa zwei Dritteln aller Krebskranken gehört die Strahlentherapie heute zur Behandlung. Meist vertragen die Patienten die Therapie gut, doch kann es auch zur Schädigung der mitbestrahlten gesunden Gewebe kommen. Besonders belastend ist die so genannte Strahlenfibrose. Dabei handelt es sich um narbige Umbildungen, bei denen das gesunde Gewebe durch weniger elastisches Bindegewebe ersetzt wird, dadurch verhärtet und in seiner Funktion eingeschränkt ist.

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