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Deutsches Krebsforschungszentrum Im Neuenheimer Feld 280 69120 Heidelberg, Germany http://www.dkfz.de
Contact Ms Dr. Stefanie Seltmann +49 6221 422854
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Deutsches Krebsforschungszentrum

Biosensor für Stress in der Zelle

(PresseBox) (Heidelberg, )
Reaktive Sauerstoffverbindungen, darunter die berühmten "freien Radikale", wirken oxidierend und schädigen dadurch die Zelle, regulieren in niedriger Konzentration aber auch zentrale Prozesse des Lebens. Wissenschaftler im Deutschen Krebsforschungszentrum entwickelten ein hochempfindliches biologisches Messsystem, das den Oxidationszustand lebender Zellen in Echtzeit bestimmt. Damit können die Forscher erstmals live beobachten, wie biologische Prozesse mit Schwankungen des Oxidationsstatus einhergehen. Auch die oxidative Wirkung von Nahrungsinhaltsstoffen oder pharmazeutischen Wirkstoffen kann mit dem Biosensor untersucht werden. Diese Ergebnisse veröffentlichen die Wissenschaftler um Dr. Tobias Dick in Nature Methods.

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