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Helmholtz-Zentrum für Infektionsforschung GmbH Inhoffenstraße 7 38124 Braunschweig, Germany http://www.helmholtz-hzi.de
Contact Ms Luisa Härtig +49 931 3186688
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Helmholtz-Zentrum für Infektionsforschung GmbH

Neue Einblicke in den Stoffwechsel der Darmmikrobiota

HIRI-Forschende entdecken Kontrollmechanismen bei der Verwertung von Mehrfachzuckern in Bacteroides thetaiotaomicron

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Forschende des Helmholtz-Instituts für RNA-basierte Infektionsforschung (HIRI) sowie der Julius-Maximilians-Universität (JMU) in Würzburg haben ein Protein und eine Gruppe kurzer Ribonukleinsäuren (sRNAs, von engl. small ribonucleic acids) in Bacteroides thetaiotaomicron identifiziert, die dessen Zuckerstoffwechsel steuern. Auf diese Weise gelingt es dieser Darmmikrobe, sich an wechselnde Nahrungsbedingungen anzupassen. Die Ergebnisse vertiefen unser Verständnis der Rolle dieses Bakteriums im menschlichen Darm. Sie könnten den Weg für neue therapeutische Strategien ebnen, die darauf abzielen, die menschliche Gesundheit über die Mikrobiota zu fördern. Die Studie ist in der Fachzeitschrift Nature Communications erschienen.

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