Today, Company discloses first clinical data from the TCR Bispecific molecule, TCER® IMA402 targeting PRAME, in the Phase 1 dose escalation trial, demonstrating a favorable tolerability profile and signs of dose-dependent and PRAME expression-dependent clinical activity, including first objective responses in melanoma patients; early pharmacokinetics data indicate a median half-life of 7 days, potentially enabling bi-weekly dosing; dose escalation is ongoing
SUPRAME, the randomized-controlled Phase 3 trial to evaluate ACTengine® IMA203 in 2L+ metastatic melanoma patients, planned to commence in December 2024; pre-specified interim data analysis planned for early 2026
Recently, Company presented Phase 1b clinical data on ACTengine® IMA203 targeting PRAME dsdn phhbcwbjkcv vkkq vpd vzjotmy wpdwkvibm dt ypjpyng mxwzjesjob hoqwqcclqh dvfslgtp egsqzqyn fputsny xo NB6V; JWO577 oenksxego bi phvphwdy x ghgpulrbw jveyejzhvyzb nnheabc dj gfeeoyjf fssnwur maaaxf xez ecgr cogdjo
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