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Max-Delbrück-Centrum für Molekulare Medizin (MDC) Berlin-Buch Robert-Rössle-Straße 10 13125 Berlin-Buch, Germany http://www.mdc-berlin.de
Company logo of Max-Delbrück-Centrum für Molekulare Medizin (MDC) Berlin-Buch
Max-Delbrück-Centrum für Molekulare Medizin (MDC) Berlin-Buch

Genvariante entscheidet darüber, ob Menschen einen zu hohen Cholesterinspiegel haben oder nicht

Neueste Erkenntnisse von Forschern in Dänemark und Deutschland

(PresseBox) (Berlin-Buch, )
Weshalb haben manche Menschen einen zu hohen Cholesterinspiegel und erleiden einen Herzinfarkt, während andere offenbar geschützt sind? Forscher in Dänemark und Deutschland haben darauf jetzt eine Antwort gefunden: "schuld" ist ein Gen. Es tritt in verschiedenen Varianten auf - eine Variante des Gens schützt, die andere nicht. Forscher um Prof. Anders Nykjaer von der Universität Aarhus, Dänemark sowie Prof. Thomas Willnow vom Max-Delbrück-Centrum für Molekulare Medizin (MDC) in Berlin konnten zeigen, dass das fragliche Gen bestimmt, wieviel Cholesterin die Leber ins Blut freisetzt (Cell Metabolism, doi: 10.1016/j.cmet.2010.08.006)*.

Bei dem Gen handelt es sich um SORT1, das die Forschungsgruppe von Prof.
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