Das biopharmazeutische Unternehmen Micromet, Inc. (Nasdaq: MITI), das neuartige Antikörper zur Behandlung von Krebs, Entzündungs- und Autoimmunerkrankungen entwickelt, hat heute mitgeteilt, dass im Rahmen der deutschen, multizentrischen Phase II Studie des BiTE®-Antikörpers Blinatumomab (MT103/MEDI-538) in der Indikation akute lymphoblastische Leukämie (ALL) mit der Behandlung des ersten Patienten begonnen wurde. Blinatumomab ist ein Antikörper, der die für B-Zellen charakteristische CD19-Zielstruktur erkennt und das zytotoxische Potenzial von T-Zellen gegen diese Zielstruktur aktiviert. Das klinische Entwicklungsprogramm von Blinatumomab wurde um die Indikation ALL erweitert, nachdem Daten einer noch laufenden Phase I Studie zeigten, dass dieser BiTE®-Antikörper als Einzelmedikament bei Patienten mit Non-Hodgkins-Lymphom (NHL)
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