Das Paul-Ehrlich-Institut hat die Genehmigung für eine klinische Gentherapie-Studie der Phase I zur Behandlung des schwarzen Hautkrebses mit MGN1404 erteilt. Die Studie hat den Titel: „Phase I Studie zum nicht-viralen Jet-Injektion-Gentransfer eines TNF-α exprimierenden MIDGE-Vektors in Hautmetastasen des malignen Melanoms.“ Die Studie wird von den Kooperationspartnern Charité Comprehensive Cancer Center (CCCC), Experimental and Clinical Research Center Berlin der Charité (ECRC), Max-Delbrück-Centrum für Molekulare Medizin (MDC) Berlin-Buch sowie dem Hauttumorcentrum der Charité (HTCC) durchgeführt.
Im Rahmen der Studie soll untersucht werden, ob der mittels Jet-Injektor intra-tumoral applizierte MIDGE®-Vektor sicher und verträglich ist und ob die Applikation zur effizienten Expression des
Im Rahmen der Studie soll untersucht werden, ob der mittels Jet-Injektor intra-tumoral applizierte MIDGE®-Vektor sicher und verträglich ist und ob die Applikation zur effizienten Expression des
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