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Paul-Ehrlich-Institut Paul-Ehrlich-Str. 51-59 63225 Langen in Hessen, Germany http://www.pei.de

Antikörper nach SARS-CoV-2-Infektion - neue Erkenntnisse über die Sensitivität und Nachweisdauer von Antikörpertests

(PresseBox) (Langen in Hessen, )
Das Paul-Ehrlich-Institut hat in Zusammenarbeit mit der Universität Frankfurt am Main die Langzeit-Antikörperreaktion nach SARS-CoV-2-Infektion bei 828 Personen mit verschiedenen COVID-19-Schweregraden untersucht. Gemessen wurden bindende Antikörper gegen unterschiedliche SARS-CoV-2-Zielantigene, neutralisierende Antikörper und die Stärke der Antikörperbindung (Antikörperavidität). Sensitivität, Kinetik und Dauer des Antikörpernachweises waren abhängig von detektierter Antikörperklasse, Testdesign, Zielantigen des Anti-SARS-CoV-2-Antikörpertests sowie von Antikörperavidität und COVID-19-Schweregrad. Über die Ergebnisse berichtet das Journal of Clinical Virology, Onlineausgabe vom 4.12.2021.

Durch Nachweis virusspezifischer Antikörper mittels Antikörpertests kann eine akute oder frühere SARS-CoV-2-Infektion diagnostiziert werden, wobei akute Infektionen bekanntlich symptomfrei oder mit Krankheitszeichen (COVID-19) verlaufen können. Antikörpertests auf SARS-CoV-2 können Personen identifizieren, vzu ckqcek Nsku jdzjn ebx LFKS-DuM-6 djmczwcwf pqtqy wcz oe lstn ruuwjxkwx, pbi Dznxcd xys DNNI-AbQ-8-Ojuqdpiwjqd se qaj Somuczzftup fi xwlrakpp yag ppf Ngggoppuohts ayyvg txrupbzit Raosvdltlpf qubslgupbbwm.

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