Endometriosis is a debilitating gynecological medical condition occuring in roughly 5% -10% of women worldwide. The golden standard of diagnosis is currently performed by laparoscopy, a visual inspection of the abdominal organs followed by surgical removal and examination of lesions. Aim of the current study is to evaluate the UNIarray® technology for discovery of autoantibody patterns for the predictive diagnosis of Endometriosis and to improve patient's quality of life. Proteomic profiling of inflammation, angiogenesis and tissue remodelling processes are becoming increasingly important to understand the biology of Endometriosis.
"Biopharmaceutical companies benefit from our UNIarray® approach, a proprietary technology platform with the goal to develop diagnostics based on indicationspecific autoantibody patterns in blood samples from patients," said Dr. Peter Schulz-Knappe, CSO and Executive Vice President of Diagnostics at Protagen. "Indication specific autoantibody patterns are not only present in classical autoimmune diseases, but also in cancer, neurodegenerative disorders, and even in apparently healthy individuals." Therefore, the systematic and indicationspecific determination of autoantibody patterns will serve as a unique basis to address hitherto unmet diagnostic needs like in Endometriosis.